The Saudi International Medical Education Conference (SIMEC) hosts the largest biannual gathering of medical educators in the Kingdom of Saudi Arabia, boosting its status as the most prominent and foremost medical education conference in the region. SIMEC 2016 marks the fifth conference in this series, continuing the legacy and positive outreach caused by SIMEC since its beginning. Many health professionals and researchers in the fields of medical and health sciences education, public health, basic, clinical and social sciences participate in this international gathering. The conference mainly covers and reports recent developments and research in the medical education field. It also covers a wide variety of continuously arising topics and issues that are of current importance and interest. These include innovations in medical education, international dimensions, and new curriculum trends.